Table 2.
Particle size, polydispersity index (PDI), ζ-potential and encapsulation efficiency (EE) of nanoliposomes loading peptides with different molecular weight (2 mg/mL)
| Sample | Particle size (nm) | Polydispersity index (PDI) | ζ-potential (mV) | EE (%) | |
|---|---|---|---|---|---|
| Peptide | Nanoliposome | ||||
| L-0 | 80.1 ± 0.8c | 0.224 ± 0.01c | – | − 1.96 ± 0.3c | – |
| L-F1 | 81.3 ± 0.6b | 0.251 ± 0.01b | − 30.1 ± 0.2b | − 7.75 ± 0.3b | 52.5 ± 2b |
| L-F2 | 81.1 ± 0.6b | 0.239 ± 0.005bc | − 30.3 ± 0.1ab | − 7.86 ± 0.1b | 59.3 ± 2a |
| L-F3 | 83.5 ± 0.5a | 0.279 ± 0.004a | − 29.9 ± 0.2a | − 8.46 ± 0.3a | 51.2 ± 3b |
Different letters in each column (a, b, c) represents a significant difference between treatments (P < 0.05) and data are shown as mean ± standard deviation (n = 3)
L-0: empty nanoliposomes; L-F1: nanoliposome loaded with < 5 kDa peptides; L-F2: nanoliposome loaded with 5–10 kDa peptide; L-F3: nanoliposomes loaded with crude peptide (2 mg/mL)