TABLE 6.

Physicochemical characteristics of optimized gel formulations.

	Formulation	Appearance	*Homogeneity	Spreadability (mm)	**Drug content in gel (%)
1	Blank gel	Clear, opaque	***	28.33 ± 0.47	Nil
2	PLGA NP gel	Clear, opaque	***	26.01 ± 0.80	Nil
3	Keto NP gel	Clear, opaque	***	29.66 ± 1.24	2
4	Keto PLGA NP gel	Clear, opaque	***	26.33 ± 0.47	2
5	Keto-drug gel	Clear, opaque	***	33.33 ± 0.47	2
6	AgNP gel	Clear, half-white	***	34.66 ± 1.24	Nil
7	Keto PLGA NP + AgNP gel	Clear, half-white	***	32.00 ± 0.50	2
8	Commercial cream***	Clear, white	***	26.33 ± 0.47	2

*Homogeneity: * = Fair, ** = Good, *** = Excellent.