TABLE 2.

Representative data from assays of 49 Lactobacillus strains to determine their capacities to resist the toxicity of TDCA at different concentrations and statistical methods used to analyze the data for each strain^a

Strain	Resistanceb	TDCA concn (mM)	Population size (107 cells ml−1) after incubation for:				ANOVA P valuec	Linear regression analysisd
			0 h	1 h	5 h	10 h		r value	P value
JCM 1068	R	0	11.8e	12.8	23.1	31.9	0.99	0.98	0.01
		1	13.5	13.0	24.8	35.4
		3	10.7	12.2	22.2	35.4
		5	14.7	10.9	24.3	36.6
ATCC 25644	R	0	13.9	14.5	31.7	33.1	0.14	0.91	0.05
		1	12.6	12.2	26.7	28.6
		3	16.9	12.6	23.9	25.6
		5	4.9	4.1	11.0	18.3
JCM 1229	S	0	9.9	10.5	24.4	31.3	0.14	−0.95	0.03
		1	10.4	12.1	13.6	12.1
		3	11.2	12.7	12.2	7.7
		5	11.8	11.6	10.2	5.7
JCM 1025	S	0	3.3	3.5	7.4	9.3	0.17	−0.86	0.20
		1	3.5	5.0	7.8	17.3
		3	4.7	5.0	3.6	2.6
		5	4.9	3.2	2.1	1.1
BCCM 9203	A	0	5.5	5.2	13.3	20.8	0.60	0.18	0.49
		1	8.0	7.6	13.3	18.1
		3	6.9	6.6	12.3	15.8
		5	6.3	6.5	10.4	5.9

^aAssayed by examining the populations in MRS broth medium containing TDCA at the concentrations indicated. The population sizes were estimated from the viable counts on MRS agar at the times indicated. 

^bR, Resistant; S, susceptible; A, ambiguous. 

^cOne-way analysis of variance (ANOVA) for four independent samples. The P value indicates the probability that the means and variance around the means for populations grown in MRS lacking TDCA differ from the means and variance around the means for populations grown in MRS containing TDCA at concentrations of 1, 3, and 5 mM (identity, r = 1.0). 

^dr is the Pearson correlation coefficient, the coefficient of correlation for data that generated slopes of lines from estimates of population-size after 0, 1, 5, and 10 h of incubation in MRS lacking and containing 5 mM TDCA (identity, r = 1.0). P is the probability (one tailed) that the correlation coefficient indicates nonidentity of the slopes of the lines generated (identity, P = 0.00). 

^eEstimated population size.