Table 1.
The characteristics of participants of each group.
| NC (n = 82) | SCD (n = 44) |
MCI (n = 51) |
AD (n = 25) |
P-valued | ||||
|---|---|---|---|---|---|---|---|---|
| Mean (SD) or % | Mean (SD) or % | P-valuea | Mean (SD) or % | P-valueb | Mean (SD) or % | P-valuec | ||
| Age | 64.37 (8) | 64.73 (7.18) | 0.995 | 66.06 (7.72) | 0.62 | 71.8 (8.6) | 2.83e−4 | 0.00055 |
| Gender (Male %) | 32.93% | 31.82% | 1 | 23.53% | 0.34 | 36% | 0.97 | 0.62 |
| Education | 11.67 (4.31) | 12.07 (3.49) | 0.94 | 10.16 (2.68) | 0.13 | 10.08 (4.76) | 0.28 | 0.029 |
| APOE4 + (%) | 23.17% | 11.36% | 0.17 | 25.49% | 0.92 | 40% | 0.16 | 0.056 |
| MMSE | 27.76 (2.22) | 27.59 (1.63) | 0.99 | 26.51 (2.05) | 0.032 | 17.24 (4.79) | 4.11e−14 | 5.07e−44 |
| MoCA_B | 25.45 (2.95) | 24.43 (2.94) | 0.38 | 22 (3.21) | 3.06e−07 | 12.32 (5.46) | 4.12e−14 | 3.22e−39 |
| ACEIII | 80.51 (11.14) | 78.98 (7.54) | 0.88 | 70.86 (9.36) | 9.04e−06 | 51.08 (16.71) | 4.65e−14 | 1.89e−24 |
NC = normal cognition; SCD = subjective or subtle objective cognitive decline; MCI = mild cognitive impairment; AD = Alzheimer's disease; MMSE = Mini-Mental State Examination; MoCA_B = Montreal cognitive assessment-basic; ACEIII = Addenbrooke's Cognitive Examination - III; SD = standard deviation.
Results presented as mean ± SD or frequencies with proportions. Quantitative and categorical characteristics differences were assessed with ANOVA and Chi-Square test, respectively.
a
P-value for comparison between SCD and NC.
b
P-value for comparison between MCI and NC.
c
P-value for comparison between AD and NC.
d
P-value for comparison among NC, SCD, MCI and AD.