TABLE 4.
IDH1 and IDH2 gene status in ICC cases.
| Adequacy | N = 90 |
| Inadequate samples | 14/90 (15.6%) |
| Adequate samples | 76/90 (84.4%) |
| Molecular alterations | N = 76 |
| IDH1 point mutations* | 15/76 (19.7%) |
| Arg132Cys | 6/76 (7.9%) |
| Arg132His | 2/76 (2.6%) |
| Arg132Val | 1/76 (1.3%) |
| Arg132Ser | 1/76 (1.3%) |
| Arg132X | 4/76 (5.2%) |
| Gly105Asn | 1/76 (1.3%) |
| IDH1105GGT SNP* | 9/76 (11.8%) |
| IDH2 Arg172X | 1/76 (1.3%) |
| IDH1-2 WT | 53/76 (69.7%) |
*2 cases showed both an IDH1 point mutation in codon 132 (Arg132Cys and Arg132His) and IDH1105GGT SNP. SNP, single nucleotide polymorphism; WT, wild type.