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. 2022 Jul 8;10:919438. doi: 10.3389/fcell.2022.919438

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Copyright © 2022 Centrone, D’Agostino, Ranieri, Mola, Faviana, Lippolis, Silvestris, Venneri, Di Mise, Valenti and Tamma.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expression of Vasopressin receptors and AQP3 in human colon biopsy. Equal amount of proteins (20 µg) of total homogenates from human colon biopsies were blotted and probed with the indicated antibodies. (A) Immunodetection revealed that V1aR protein expression is significantly decreased in tumors compared to the normal colon mucosa. (B–C) Immunodetection revealed that V2R and AQP3 protein expression is not altered in human colon adenocarcinoma. Data are shown as mean ± S.E.M. and analyzed by Student’s t-test (**p < 0.01 vs. normal colon mucosa).