Table 1.
Baseline Characteristics, Clinical and Laboratory Indicators of Patients with COVID-19
| Variables | Re-Positive (n=18) | Non-Re-Positive (n=126) | P-value |
|---|---|---|---|
| Age (years) | 52.00 (43.50–63.75) | 46.50 (37.00–56.00) | 0.109 |
| Gender-n (%) | 0.850 | ||
| Male | 10 (55.6) | 67 (53.2) | |
| Female | 8 (44.4) | 59 (46.8) | |
| BMI (kg/m2) | 23.40 (22.20–26.90) | 24.50 (22.00–26.30) | 0.562 |
| Heart rate (/min) | 89.00 (81.75–97.25) | 82.00 (75.00–90.00) | 0.011 |
| Respiratory rate (/min) | 19.00 (18.00–19.75) | 19.00 (18.00–20.00) | 0.978 |
| Admission since onset (days) | 4.50 (3.00–7.00) | 6.00 (4.00–10.00) | 0.095 |
| Length of hospitalization (days) | 21.50 (17.00–29.75) | 21.50 (13.00–27.75) | 0.556 |
| Severe-n (%) | 6 (33.3) | 30 (23.8) | 0.561 |
| Clinical symptoms-n (%) | |||
| Fever | 13 (72.2) | 91 (72.2) | 1.000 |
| Cough | 6 (33.3) | 59 (46.8) | 0.282 |
| Comorbidities-n (%) | |||
| Hypertension | 4 (22.2) | 18 (14.3) | 0.599 |
| Diabetes mellitus | 3 (16.7) | 11 (8.7) | 0.524 |
| Hepatitis | 3 (16.7) | 4 (3.2) | 0.042 |
| Lung CT-n (%) | |||
| Lung lobes | 2.00 (1.00–4.00) | 3.50 (2.00–5.00) | 0.105 |
| Patchy/GGO | 14 (87.5) | 97 (95.1) | 1.000 |
| Consolidation | 6 (37.5) | 45 (44.1) | 0.843 |
| Fibrous stripes | 4 (25.0) | 33 (32.4) | 0.943 |
| Treatment-n (%) | |||
| Abidol | 15 (83.3) | 68 (54.0) | 0.018 |
| Antibiotic | 9 (50.0) | 31 (24.6) | 0.024 |
| Oseltamivir | 7 (38.9) | 21 (16.7) | 0.056 |
| Immunoglobulin | 7 (38.9) | 33 (26.2) | 0.261 |
| Methylprednisolone | 8 (44.4) | 35 (27.8) | 0.148 |
| Interferon | 18 (100.0) | 125 (99.2) | 1.000 |
| Kaletra | 18 (100.0) | 124 (98.4) | 1.000 |
| Laboratory index | |||
| WBC (×109/L) | 5.55 (4.93–6.75) | 5.30 (4.30–6.60) | 0.361 |
| Neutrophil count (×109/L) | 3.90 (3.12–5.40) | 3.40 (2.60–4.60) | 0.268 |
| Lymphocyte count (×109/L) | 1.10 (0.72–1.48) | 1.20 (0.80–1.60) | 0.450 |
| PLT (×109/L) | 201.50 (178.25–253.50) | 204.00 (161.00–247.00) | 0.935 |
| CRP (mg/L) | 6.85 (1.30–20.90) | 10.30 (3.95–26.20) | 0.454 |
| SAA (mg/L) | 22.70 (7.95–297.70) | 109.45 (21.62–265.30) | 0.306 |
| Crea (μmol/L) | 75.00 (68.25–93.25) | 74.00 (65.00–88.00) | 0.236 |
| Urea (mmol/L) | 4.51 (4.00–6.60) | 3.96 (3.24–5.09) | 0.050 |
| eGFR (mL/min) | 88.00 (74.75–97.00) | 97.00 (84.00–106.00) | 0.034 |
| Glu (mmol/L) | 6.20 (5.07–8.86) | 6.57 (5.55–8.47) | 0.555 |
| TG (mmol/L) | 1.15 (0.72–1.32) | 1.43 (1.01–2.19) | 0.015 |
| TyG index | 3.71 (3.51–4.02) | 3.90 (3.74–4.08) | 0.036 |
| TC (mmol/L) | 3.92 (3.59–4.51) | 3.86 (3.47–4.45) | 0.846 |
| HDL-C (mmol/L)] | 1.15 (0.93–1.25) | 1.01 (0.86–1.16) | 0.123 |
| LDL-C (mmol/L) | 2.64 (2.16–3.18) | 2.47 (2.14–3.01) | 0.715 |
| ApoA1 (g/L) | 1.09 (0.96–1.26) | 1.25 (0.96–1.44) | 0.167 |
| ApoB (g/L) | 0.84 (0.70–0.99) | 0.81 (0.67–1.00) | 0.910 |
| C3 (g/L) | 1.27 (1.02–1.49) | 1.35 (1.20–1.50) | 0.207 |
| C4 (g/L) | 0.36 (0.28–0.44) | 0.38 (0.33–0.46) | 0.272 |
| C1q (mg/L) | 209.00 (175.50–231.25) | 234.00 (203.00–252.50) | 0.023 |
| IL-2 (pg/mL) | 1.45 (0.63–2.71) | 1.35 (0.91–2.16) | 0.844 |
| IL-4 (pg/mL) | 1.52 (1.04–2.21) | 1.52 (0.96–2.19) | 0.776 |
| IL-6 (pg/mL) | 6.75 (4.34–15.04) | 9.37 (3.68–22.73) | 0.965 |
| IL-10 (pg/mL) | 3.71 (2.38–7.20) | 3.58 (2.79–5.80) | 0.825 |
| CD4+ T cells (/μL) | 379.50 (202.04–494.89) | 347.76 (244.39–524.51) | 0.696 |
| CD8+ T cells (/μL) | 212.57 (151.92–330.90) | 252.37 (164.21–345.91) | 0.371 |
| CD19 cells (/μL) | 165.82 (85.50–222.02) | 135.69 (95.17–206.99) | 0.676 |
| NK cells (/μL) | 166.76 (135.42–250.66) | 195.82 (125.59–243.54) | 0.658 |
Note: The bold values was P<0.05.
Abbreviations: Patchy/GGO, patchy opacity and ground-glass opacity; WBC, white blood cell count; PLT, platelet; CRP, C-reactive protein; SAA, serum amyloid A; Crea, creatinine; Urea, urea nitrogen; eGFR, estimated glomerular filtration rate; Glu, glucose; TG, triglyceride; TyG index, triglyceride-glucose index; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; ApoA1, apolipoprotein A1; ApoB, apolipoprotein B; C3, complement C3; C4, complement C4; C1q, complement C1q; IL-2, interleukin-2; IL-4, interleukin-4; IL-6, interleukin-6; IL-10, interleukin-10.