Table 4.
Logistic Regression Analysis for Predictive Power of circPTP4A2 and circTLK2
| Variable | Univariate Analysisa | Multivariate Analysisb | ||
|---|---|---|---|---|
| OR (95% CI) | P-value | OR (95% CI) | P-value | |
| AISc | ||||
| circPTP4A2 | 3.204 (2.183–4.705) | <0.001 | 2.788(1.876–4.145) | <0.001 |
| circTLK2 | 2.576 (1.768–3.754) | <0.001 | 2.480(1.676–3.670) | <0.001 |
| TIAc | ||||
| circPTP4A2 | 1.782 (1.142–2.780) | 0.011 | 1.628(1.036–2.560) | 0.035 |
| circTLK2 | 1.877 (1.230–2.863) | 0.003 | 1.736(1.141–2.639) | 0.010 |
| AISd | ||||
| circPTP4A2 | 1.799 (1.291–2.505) | 0.001 | 1.713(1.220–2.405) | 0.002 |
| circTLK2 | 1.373 (1.045–1.804) | 0.023 | 1.429(1.078–1.894) | 0.013 |
Notes: aOnly one of the candidate circRNAs was included in the model. bThe age, sex, vascular risk factors and biochemical indexes were adjusted in the model. cThe reference category was the HCs group. dThe reference category was the TIA group.
Abbreviations: AIS, acute ischemic stroke; CI, confidence interval; HCs, healthy control subjects; OR, odds ratio; TIA, transient ischemic attack.