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The logistic regression model based on four metabolites for predicting PROM in early pregnancy serum samples. (A) The ROC curve of the combination of four compounds in serum. Violin plots (medians with quartiles) are shown of four compounds, Cer 40:0; O2 (B), sphingosine (C), isohexanal (a fatty aldehyde) (D) and PC O-38:4 (a glycerophospholipid) (E), with significant differences between the PROM and healthy cohorts. The forest plot of the AUC values of differential compounds (F).
