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. 2022 Jul 8;13:858851. doi: 10.3389/fendo.2022.858851

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Copyright © 2022 Wang, Zhang, Liang, Zhou, Huang, Zhao and Luo

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MR estimates of the associations between PUFAs and BMD. The x-axis is the effects of PUFAs on BMD values. The vertical dashed line is the reference at effect = 0. The y-axis presents different BMD types, which are highlighted in different colors. Different MR methods are displayed with different line types. MR, Mendelian randomization; BMD, bone mineral density; FN-BMD, femoral neck BMD; LS-BMD, lumbar spine BMD; FA-BMD, forearm BMD; TB-BMD, total body BMD; SNPs, single nucleotide polymorphisms; IVW, inverse variance weighted; SE, standard error; CI, confidence interval.