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. 2022 Jul 8;13:858851. doi: 10.3389/fendo.2022.858851

Table 2.

MR-PRESSO estimates of the causal effects of PUFAs on BMD.

Exposures Outcomes Number Effect MR p-value MR-PRESSO
of
SNPs Global test p-value
Omega3 LS-BMD 22 −0.079 0.118 0.499
FN-BMD 22 −0.0002 0.995 0.828
FA-BMD 24 −0.075 0.309 0.791
TB-BMD 36 −0.042 0.146 0.174
Omega6 LS-BMD 29 −0.025 0.577 0.083
FN-BMD 29 0.001 0.972 0.992
FA-BMD 30 0.065 0.272 0.783
TB-BMD 45 −0.0515 0.012 0.541
Ratio of Omega6 to Omega3 LS-BMD 18 0.05 0.414 0.293
FN-BMD 18 0.029 0.507 0.643
FA-BMD 20 −0.032 0.716 0.638
TB-BMD 26 0.032 0.352 0.317