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. 2022 Jul 8;13:910868. doi: 10.3389/fendo.2022.910868

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Copyright © 2022 Cheng, Yao, Zhou, Sun, Meng, Wang, Xing, Wan and Hua

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Changes in MafA expression were associated with METTL3-regulated GSIS from NIT-1 cells. (A) Immunoblot of MafA expression in NIT-1 cells transfected with si-METTL3 + pcDNA or si-METTL3 + pcDNA MafA. (B) Quantification of the immunoblot in (A). (C) The GSIS index of the cells described in (A). (D) Immunoblot of MafA expression in NIT-1 cells transfected with Ad-METTL3 + si-NC or Ad-METTL3 + si-MafA and treated with 1 mM MG for 24 h. (E) Quantification of the immunoblot in (D). (F) The GSIS index of the cells described in (D). Results are presented as means ± SD of n = 3‐4 independent experiments. ^* p < 0.05.