Table 2.
Parameters | With chitosan | Without chitosan |
---|---|---|
Cmax (ng/mL) | 1279.3 ± 557.9∗ | 635.8 ± 128.3 |
Tmax (min) | 120.0∗ | 300.0 |
t1/2,λz (min) | 389.9 ± 51.5 | 333.0 ± 86.4 |
AUC0-t (μg·min/mL) | 724.9 ± 232.5∗ | 439.2 ± 123. |
AUC0-∞ (μg·min/mL) | 787.8 ± 248.5∗ | 451.9 ± 136.6 |
CL/F (mL/min/kg) | 27.9 ± 10.4 | 35.7 ± 23.8 |
Vd,λz/F (mL/kg) | 15612.1 ± 5507.6 | 16794.1 ± 12638.5 |
F (%) | 174 |
Notes: Each value represents the mean ± SD (n = 5). Significant differences were accepted at p < 0.05 (∗).