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. 2022 Jun 6;298(8):102109. doi: 10.1016/j.jbc.2022.102109

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© 2022 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Comparison of the surface of Ghcol and ColG. The surface of Ghcol (A and C) and ColG (B and D) with Gly-Glu-Hyp peptides. The peptides are placed on the active site of ColG after fitting the peptidase domain of ColG to Ghcol. A and B, the surface is colored in pink and cyan for the peptidase upper-half (C1) and lower-half (C2) subdomain, respectively, except for acidic (red) and basic (blue) amino acids. C and D, the electrostatic surface potential density is colored gradient from red (−10 kT/e) to blue (10 kT/e). Ghcol, collagenase from Grimontia hollisae strain 1706B.