Skip to main content
. 2022 Jun 25;298(8):102195. doi: 10.1016/j.jbc.2022.102195

Figure 1.

Figure 1

Sulfonolipids are structurally related to sphingolipids.A, sulfonolipid (sulfobactin B) is structurally related to ceramide-1-phosphate. Sulfobactin A has an amide-linked 3-hydroxy-acyl chain. B, capnine is a nonhydrolyzable analog of sphingosine-1-phosphate. C, the sulfonolipid biosynthetic pathway is analogous to the bacterial sphingolipid biosynthetic pathway (28). The first step is carried out by a condensing enzyme belonging to the α-oxoamine synthase (AOS) protein superfamily to form 3-ketocapnine (2-amino-3-keto-15-methylhexadecane-1-sulfonic acid) (SulA). There are two genes encoding members of this protein family in A. finegoldii (alfi_1224 and alfi_1465). SulA, cysteate acyl-ACP transferase.