Table 3.
Kinetic models and their calculated regression coefficient for Epirubicin release from the nanocarriers.
| Model | Equation | Epi | Epi-Nio; 7.4 | Epi-Nio; 5.4 | Epi-Nio-HA; 7.4 | Epi-Nio-HA; 5.4 |
|---|---|---|---|---|---|---|
| Zero-Order | Ct = C0 – K0.t | R2 = 0.4441 | R2 = 0.7965 | R2 = 0.7092 | R2 = 0.8297 | R2 = 0.7907 |
| First-Order | Ln Ct/C0 = – k1.t | R2 = 0.8737 | R2 = 0.8485 | R2 = 0.8370 | R2 = 0.8686 | R2 = 0.8661 |
| Korsmeyer–Peppas model | Mt/M∞ = Ktn | R2 = 0.7051 n = 0.3842 | R2 = 0.9598 n = 0.4755 | R2 = 0.9197 n = 0.4062 | R2 = 0.9729 n = 0.4822 | R2 = 0.9452 n = 0.4556 |
| Higuchi | C = KH√t | R2 = 0.6149 | R2 = 0.9262 | R2 = 0.8646 | R2 = 0.9475 | R2 = 0.9228 |