Table 5.

Renal and liver enzymes activity assessment.

Enzyme	Healthy Control	Cancer Control	Epi	Epi-Nio	Epi-Nio-HA
BUN (mg/dL)	21.76 ​± ​2.02	35.43 ​± ​1.21	27.76 ​± ​1.42	25.14 ​± ​1.65	22.66 ​± ​2.14
Creatinine (mg/dL)	0.5 ​± ​0.1	1.67 ​± ​0.12	1.0 ​± ​0.21	0.7 ​± ​0.13	0.6 ​± ​0.24
AST (U/L)	105 ​± ​1.99	127.76 ​± ​2.55	122.76 ​± ​1.72	113.54 ​± ​2.76	103.86 ​± ​1.96
ALT (U/L)	115 ​± ​1.12	132.15 ​± ​3.99	121.56 ​± ​3.77	118.09 ​± ​3.65	117.55 ​± ​2.87
ALP (U/L)	267 ​± ​2.43	488.40 ​± ​3.66	311.43 ​± ​5.65	278.05 ​± ​4.51	234.78 ​± ​3.08