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. 2022 Jul 8;13:951582. doi: 10.3389/fimmu.2022.951582

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Copyright © 2022 Feng, Xu, Dai, Yin, Zhang and Shen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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WGCNA in the GPL570 meta-cohort and TCGA-OV cohort. (A) Scale independence and mean connectivity in the GPL570 meta-cohort. (B) Scale independence and mean connectivity in TCGA-OV cohort. (C) Gene dendrogram and modules before merging in the GPL570 meta-cohort. (D) Gene dendrogram and modules before merging in TCGA-OV cohort. (E) Pearson correlation analysis of merged modules and CAF score in the GPL570 meta-cohort. (F) Pearson correlation analysis of merged modules and CAF score in TCGA-OV cohort. (G) Scatterplot of MM and GS from the brown module in the GPL570 meta-cohort, including CAFs_EPIC (i) and Fibroblasts_MCPcounter (ii). (H) Scatterplot of MM and GS from the blue module in TCGA-OV cohort, including CAFs_EPIC (i) and Fibroblasts_MCPcounter (ii). WGCNA, Weighted Gene Co-expression Network Analysis; CAFs, Cancer-Associated Fibroblasts; GS, Gene Significance; MM, Module Membership.