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. 2022 Jul 8;13:951582. doi: 10.3389/fimmu.2022.951582

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Copyright © 2022 Feng, Xu, Dai, Yin, Zhang and Shen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Functional analyses and construction of the CAF-based signature. (A) The hub CAF-related genes were overlapped in the brown module and the blue module. (B) GO enrichment analysis. (C) KEGG enrichment analysis. (D) Univariate Cox regression analysis of common hub genes (P < 0.001). (E) LASSO regression analysis. (F) Kaplan–Meier analysis of different cohorts. On the left is GPL570 meta-cohort; on the right is TCGA-OV cohort. CAFs, Cancer-Associated Fibroblasts; GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; LASSO, Least Absolute Shrinkage and Selection Operator.