RA	rheumatoid arthritis
GPCRs	G protein-coupled receptors
NSAIDs	non-steroidal anti-inflammatory drugs
GDP	guanosine diphosphate
GTP	guanosine triphosphate
cAMP	cyclic adenosine monophosphate
PKC	protein kinase C
CCR	C-C motif chemokine receptor
CXCR	C-X-C motif chemokine receptors
XCR1	X-C motif chemokine receptor 1
CX3CR1	C-X3-C motif chemokine receptor 1
anti-CCP	anti-cyclic citrullinated peptide
DAS28	the disease activity score-28
RF	rheumatoid factor
FLSs	fibroblast-like synoviocytes
TNF&alpha	tumor necrosis factor &alpha
MMP	matrix metalloproteinase
CIA	the collagen-induced arthritis
IFN	interferon
CXCL10, RANKL	receptor activator of nuclear factor kappa-B ligand
CKLF1	chemokine-like factor 1
CRP	C-reactive protein
ESR	erythrocyte sedimentation rate
E2F2	E2F transcription factor 2
FOXP	forkhead box P
STAT5	signal transducer and activator of transcription 5
ROR	RAR-related orphan nuclear receptor
LPS	lipopolysaccharides
PGC1	proliferator-activated receptor gamma coactivator 1
ACPA	anti-cyclic citrullinated peptide antibody
ERK	extracellular signal-regulated kinase
VLA-4	very late activation antigen 4
VCAM-1	vascular cell adhesion molecule 1
SDF-1	stromal cell-derived factor 1
TLR	Toll-like receptor
NF-kB	nuclear factor kappa-light-chain-enhancer of activated B cells
Tfh	follicular helper T
P-gp	P-glycoprotein
Tfr	follicular regulatory T
ROS	reactive oxygen species
Bregs	regulatory B cells
JNK	Janus kinase
MAPK	mitogen-activated protein kinase
MNCs	mononuclear cells
MC	melanocortin
NOS2	nitric oxide synthase 2
a-MSH	alpha-Melanocyte-stimulating hormone
sTNFr	soluble tumor necrosis factor receptor
PUFA	polyunsaturated fatty acids
TAK1	transforming growth factor-&beta activated kinase 1
HMG-1	high mobility group protein 1
IL	interleukin
MCP-1	monocyte chemoattractant protein 1
ICAM-1	intercellular adhesion molecule 1
VCAM-1	vascular cellular adhesion molecule 1
VEGF	vascular endothelial growth factor
PBMC	peripheral blood mononuclear cell
KKS	kallikrein-kinin system
pKal	prekallikrein
FXII	factor XII
HK	high-MW kininogen
sRANKL	soluble receptor activator of nuclear factor kappa B ligand
PI3Ks	phosphoinositide 3-kinases
PKB	protein kinase B
FPRL1	formyl peptide receptor-like 1
A-SAA	acute-phase serum amyloid A
GRK2	G protein-coupled receptor kinase 2