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. 2022 May 13;14(2):494–511. doi: 10.1016/j.jcmgh.2022.05.002

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© 2022 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Main KEGG pathways and GO terms enriched by DEGs between the Rosa26-LSL-IE2^+/- and the Rosa26-LSL-IE2^+/-, cre group. (A) Top 20 up-regulation KEGG pathways. (B) Top 5 up-regulation GO terms, including BP, CC, and MF. (C) Top 20 down-regulation KEGG pathways. (D) Top 5 down-regulation GO terms, including BP, CC, and MF. BP, biological process, CC, cellular component, HTLV-1, human T-lymphotropic virus type 1; Jak-STAT, janus kinase-signal transducer and activator of transcription; MAPK, mitogen-activated protein kinase; MF, molecular function; PI3K-Akt, phosphatidylinositol 3 kinase (PI3K)/protein kinase B (AKT); PPAR, peroxisome proliferator-activated receptor.