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. 2022 Jul 22;12:12523. doi: 10.1038/s41598-022-15969-y

Table 1.

Patients with COVID-19 characteristics.

Mild (n = 59) Severe (n = 98) Total (n = 157) p value
Age—years 0.4451
Mean (SD) 66.4 (18.6) 68.5 (14.7) 67.7 (16.2)
Range 20–92 35–96 20–96
Female—n (%) 26 (44.1%) 42 (42.9%) 68 (43.3%) 0.8822
Duration of symptoms—days < 0.0011
Mean (SD) 11.1 (6.0) 16.8 (10.182) 14.7 (9.3)
Range 1–32 2–47 1–47
Missing values 1 1 2
Medical history—n (%)
Thrombosis 9 (15.3%) 8 (8.2%) 17 (10.8%) 0.1662
Heart failure 2 (3.4%) 6 (6.1%) 8 (5.1%) 0.4512
Stroke 5 (8.5%) 7 (7.1%) 12 (7.6%) 0.7612
Coronary heart disease 7 (11.9%) 6 (6.1%) 13 (8.3%) 0.2062
Diabetes 14 (23.7%) 19 (19.4%) 33 (21.0%) 0.5182
High blood pressure 31 (52.5%) 45 (45.9%) 76 (48.4%) 0.4212
Chronic renal failure 6 (10.2%) 6 (6.1%) 12 (7.6%) 0.3552
Chronic respiratory disease 7 (11.9%) 8 (8.2%) 15 (9.6%) 0.4452
Cancer 9 (15.3%) 17 (17.3%) 26 (16.6%) 0.7332
Anticoag. treatment—n (%) 31 (53.4%) 77 (78.6%) 108 (69.2%) 0.0012
Missing values 1 0 1
Invasive ventilation—n (%) 0 (0.0%) 35 (35.7%) 35 (22.3%) < 0.0012
Thrombotic events—n (%) 1 (2.6%) 7 (8.3%) 8 (6.6%) 0.2392
Missing values 21 14 35
PMN (G/L) < 0.0011
Mean (SD) 3.943 (1.7) 6.8 (4.0) 5.7 (3.6)
Range 1.2–11.0 1.0–20.0 1.0–20.0
Missing values 1 0 1
Lymphocytes (G/L) 0.8611
Mean (SD) 1.3 (0.5) 1.3 (0.8) 1.3 (0.7)
Range 0.4–3.0 0.1–3.9 0.1–3.9
Missing values 1 0 1
NLR < 0.0011
Mean (SD) 3.6 (2.3) 8.0 (8.8) 6.4 (7.4)
Range 0.7–11.2 0.9–60.000 0.7–60.0
Missing values 1 0 1
Eosinopenia—n (%) 25 (43.1%) 67 (68.4%) 92 (59.0%) 0.0022
Missing values 1 0 1
Death—n (%) 1 (2.6%) 18 (21.7%) 19 (15.7%) 0.0072
Missing values 21 15 36

PMN polymorphonuclear neutrophils, NLR neutrophil–lymphocyte ratio, 1Student’s t test, 2Pearson’s Chi-squared test.