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. 2022 Jul 22;158(5):415–434. doi: 10.1007/s00418-022-02140-x

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Fig. 6 — The diagram demonstrates the role of inflammation (with emphasis on IL-6) in wound healing, cancer and severe/critical COVID-19 infection. While wound re-epithelization arrests the activity of granulation tissue and reduces inflammation, this negative feedback fails to act in the case of cancer and severe/critical COVID-19, worsening the prognosis of patients