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. 2022 Jan 11;17(5):e202100679. doi: 10.1002/cmdc.202100679

Table 1.

Inhibition values by 5‐substituted 2‐pyrrol‐1‐benzoic acid derivatives (18) determined using the coupled photometric assay with purified PfIspD.

graphic file with name CMDC-17-0-g011.jpg

Compd

R

IC50m]*

1

NO2

271±24

2

H

>500

3

Cl

263±35

4

Br

117±20

5

I

208±37

6

CH3

>500

7

−OCH3

>500

8

−NHCOCH3

>500