Figure 2.
A and B, Variation in disease activity using the Birmingham Vasculitis Activity Score (BVAS) (A) and daily dose of prednisone equivalents (B) among patients with eosinophilic granulomatosis with polyangiitis receiving mepolizumab 100 mg every 4 weeks and those receiving mepolizumab 300 mg every 4 weeks. C and D, Respiratory outcomes in patients during mepolizumab treatment. Kaplan–Meier curves show the occurrence of asthma exacerbations (C) and ear, nose, and throat (ENT) exacerbations (D). E and F, Variation in the forced expiratory volume in 1 second (FEV1) (E) and eosinophil count (F). Values in A, B, E, and F are the median and interquartile range.* = P < 0.05; ** = P < 0.01, versus baseline.