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Change from baseline in serum phenylalanine levels in this study and a Phase 3 clinical trial
| Study | Time point | Mean (SD) change from baseline, mg/dL |
|---|---|---|
| Current study† | Week 6 (n = 15) | –6.8 (5.5) |
| At final observation (n = 84) | –6.3 (6.5) | |
| PKU‐003‡ 4 | Week 6 (n = 41) | –3.9 (4.2) |
†Baseline was defined as the serum phenylalanine level at the BH4 loading test; ‡Conducted in patients with phenylketonuria.
SD, standard deviation.
