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SARS-CoV-2 replication cycle and the autophagy-lysosome system in the host cells. The shielded area shows the 6 steps of the viral replication cycle of SARS-CoV-2, and the link with the autophagy-lysosome pathway. The red boxes indicate the therapeutics under development (in clinical trials) against COVID-19 with relevance to the autophagy- lysosome pathway.
