TABLE 1.
Baseline demographical and clinical data of patients in the two groups
| Variates | hvKP group (n = 114) | cKP group (n = 111) | p |
|---|---|---|---|
| Sex (male) | 74 (64.9%) | 66 (59.5%) | 0.413 |
| Age (years) | 63 (55, 73) | 66 (53, 72) | 0.294 |
| White blood cell (*109/L) | 11.9 (8.8, 15.9) | 12.6 (11.0, 16.6) | 0.27 |
| Percentage of neutrophil (%) | 85 (79, 90) | 84 (78, 88) | 0.291 |
| Platelet (*109/L) | 226 (129, 311) | 194 (142, 295) | 0.465 |
| Albumin (g/L) | 28 (18, 32) | 30 (26, 33) | 0.003 |
| Total bilirubin (μmol/L) | 23 (12, 31) | 22 (13, 33) | 0.396 |
| Serum creatinine (μmol/L) | 44 (33, 67) | 48 (36, 65) | 0.859 |
| PCT (ng/ml) | 17 (3, 38) | 5 (1, 20) | 0.002 |
| CRP (mg/L) | 126 (46, 174) | 120 (43, 200) | 0.423 |
| Troponin I (ng/ml) | 0.1 (0.1, 0.3) | 0.1 (0.1, 0.6) | 0.524 |
| NT‐proBNP (Pg/ml) | 464 (232, 868) | 288 (223, 810) | 0.112 |
| APACHE II (points) | 6 (5, 9) | 7 (5, 8) | 0.226 |
| SOFA (points) | 3 (2, 5) | 2 (1, 3) | <0.001 |
| NUTRIC (points) | 2 (1, 2) | 2 (1, 2) | 0.378 |
| Total length of hospital stay (d) | 21 (12, 31) | 21 (14, 28) | 0.227 |
| Length of ICU stay (d) | 15 (8, 17) | 18 (10, 18) | 0.386 |
| Duration of mechanical ventilation (h) | 12 (8, 10) | 13 (11, 15) | 0.462 |
| Time using antibiotics (d) | 13 (7, 16) | 14 (9, 18) | 0.333 |
| Hospital infection | 28 (60.9%) | 18 (39.1%) | 0.138 |
| Targeted single drug anti‐infection | 60 (52.6%) | 9 (8.1%) | <0.001 |
| Combined with sepsis | 34 (29.8%) | 43 (38.7%) | 0.164 |
| Combined with septic shock | 19 (16.7%) | 9 (8.1%) | 0.04 |
| 28‐day survival | 98 (86.0%) | 104 (93.7%) | 0.077 |
Notes: The length of ICU stay, duration of mechanical ventilation and troponin were normally distributed. However, the standard deviation was greater than the mean value; hence, a nonparametric test was used.
Abbreviations: APACHE, Acute Physiology, Age, Chronic Health Evaluation; cKP, classic Klebsiella pneumoniae PCT = procalcitonin; CRP, C‐reactive protein; hvKP, hypervirulent Klebsiella pneumoniae; ICU, intensive care unit; NT‐proBNP, N‐terminal pro‐brain natriuretic peptide; NUTRIC, Nutrition Risk in the Critically Ill; SOFA, sequential organ failure assessment.