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. 2022 Jul 8;9:915896. doi: 10.3389/fvets.2022.915896

Figure 2.

Figure 2

Photomicrographs of cryosections of canine skin showing cannabinoid receptor 2 (CB2R) immunoreactivity (IR) in the tissues of the healthy dogs (CTRL) (a–c) and in the dogs with atopic dermatitis (AD) (d–i). (a–c) The white arrows indicate the DAPI-labeled nuclei of the keratinocytes showing moderate CB2R-IR of the cytoplasm and cell membrane. The open arrows indicate the DAPI-labeled nuclei of vascular endothelial cells of the dermis showing bright CB2R-IR. (d–i) The white arrows indicate the DAPI-labeled nuclei of the keratinocytes of the dogs with AD showing bright CB2R-IR. The open arrows indicate the DAPI-labeled nuclei of the vascular endothelial cells of the dermis showing bright CB2R-IR. Bar, 50 μm.