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Photomicrographs of cryosections of canine skin showing G protein-coupled receptor 55 (GPR55) immunoreactivity (IR) in the tissues of the healthy dogs (CTRL) (a–c) and in the dogs with atopic dermatitis (AD) (d–f). (a–c) The white arrows indicate the DAPI-labeled nuclei of the keratinocytes showing moderate cytoplasmic GPR55-IR. (d–f) The white arrows indicate some DAPI-labeled nuclei of the cells of the suprabasal layer showing moderate-to-bright GPR55-IR. Bar, 50 μm.
