Table 1.
Ongoing and completed randomized trials assessing atrial fibrillation screening
| Study | Number randomized | Screening intervention | Population |
|---|---|---|---|
| Studies cited in the current report | |||
| LOOP3 | 6004 | Implanted monitor | Age ≥70 with risk factors, Denmark |
| REHEARSE-AF4 | 1001 | Hand-held ECG, BID for 1 year | Age 65 + risk factors, UK/Wales |
| SCREEN-AF5 | 822 | 14-day ECG Patch, Twice | Age ≥75 with hypertension, Canada/Germany |
| STROKESTOP6 | 28 768 | Hand-held ECG, BID for 14 days | Age 75 and 76, Sweden |
| Completed trials without published stroke outcomes and/or conducted in post-stroke population | |||
| Find-AF NCT01855035 | 398 | 10-day Holter, 0, 3, and 6 months | Post-stroke, Germany |
| MonDAFIS NCT02204267 | 3470 | 7-day Holter, once | Post-stroke, Germany |
| mSTOPS NCT02506244 | 2659 | 12-day ECG Patch, twice | Age >75 or <75 with risk factors, USA |
| PerDIEM NCTT02428140 | 300 | Implanted monitor | Post-stroke, Canada |
| VITAL-AF NCT03515057 | 35 308 | Hand-held ECG, once | Age ≥65, USA |
| Ongoing trials | |||
| AMALFI ISRCTN15544176 | 5029 | 14-day ECG patch, once | Age ≥65 with risk factors, UK |
| DANCAVAS ISRCTN12157806 | 79 000 | 3-lead ECG, once | Men, age 60–74, Denmark |
| FIND-AF2 (high risk) NCT04371055 | 1040 | Implanted monitor | Post-stroke, Germany |
| FIND-AF2 (low risk) NCT04371055 | 4160 | 7-day Holter, once | Post-stroke, Germany |
| GUARD-AF NCT04126486 | 11 931 | 14-day ECG Patch, once | Age ≥70, USA |
| Heartline NCT04276441 | 150 000 | ECG Watch | Age ≥65, USA |
| SAFER-Internal Pilot ISRCTN16939438 | 14 082 | Hand-held ECG, QID for 21 days | Age ≥70, UK |
| SAFER-UK ISRCTN72104369 | 100 418 | Hand-held ECG, QID for 21 days | Age ≥70, UK |
| SAFER-AUS ISRCTN72104369 | 2100 | Hand-held ECG, QID for 21 days | Age ≥70, Australia |
| STROKESTOP II NCT02743416 | 28 712 | Hand-held ECG, QID for 14 days | Age 75/76 with elevated NT-ProBNP, Sweden |