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. 2022 Feb 10;70(6):1009–1026. doi: 10.1002/glia.24145

TABLE 1.

Phagocytic targets (dead cells) and responsible phagocytic receptors

Astrocytes    Microglia
Dead cell   Dead cell
AXL Konishi et al., 2020   AXL

Fourgeaud et al., 2016

Tufail et al., 2017

Ayata et al., 2018

MERTK Konishi et al., 2020   MERTK

Fourgeaud et al., 2016

Tufail et al., 2017

Ayata et al., 2018

Diaz‐Aparicio et al., 2020

BAI1 Park et al., 2007   BAI1 Mazaheri et al., 2014
MEGF10

Tasdemir‐Yilmaz & Freeman, 2013

Iram et al., 2016

Morizawa et al., 2017

  αvβ3/5 integrin

Liu et al., 2013

Fuller et al., 2018

  TREM2 Takahashi et al., 2005
  CR3 Silverman et al., 2019
Dystrophic or degenerated myelin   Dystrophic or degenerated myelin
LRP1

Gaultier et al., 2009

Ponath et al., 2017

  LRP1 Gaultier et al., 2009
αvβ3/5 integrin Mills et al., 2015   AXL Hoehn et al., 2008
  MERTK Shen et al., 2021
  TREM2

Cantoni et al., 2015

Cignarella et al., 2020

  CR3

Bruck & Friede, 1990

Liu et al., 2020