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. 2022 Feb 10;70(6):1009–1026. doi: 10.1002/glia.24145

TABLE 2.

Phagocytic targets (live cells) and responsible phagocytic receptors

Astrocytes    Microglia
   Live neuron
  MERTK Neher et al., 2013
  LRP1 Fricker et al., 2012
  αvβ3/5 integrin

Fricker et al., 2012

Neniskyte & Brown, 2012

Neher et al., 2013

  CR3 Anderson et al., 2019
Live synapse    Live synapse
MERTK Chung et al., 2013   MERTK

Chung et al., 2013

Park et al., 2021

MEGF10

Chung et al., 2013

Lee et al., 2021

  TREM2

Filipello et al., 2018

Scott‐Hewitt et al., 2020

  CR3

Schafer et al., 2012

Hong et al., 2016

  GPR56

Li et al., 2020

Li et al., 2021

Live axon    Live axon
?

Nguyen et al., 2011

Davis et al., 2014

  CR3 Lim & Ruthazer, 2021
  ? Maeda et al., 2010
   Live neuronal or glial progenitor/precursor cell
  CR3 VanRyzin et al., 2019
  ?

Cunningham et al., 2013

Nelson et al., 2017

Live astrocyte    Live astrocyte
? Punal et al., 2019   ? Punal et al., 2019
   Live astrocytic endfeet
  ? Haruwaka et al., 2019
   Live myelin
  ?

Maeda et al., 2010

Hughes & Appel, 2020

   Live oligodendrocyte progenitor cell
  ? Nemes‐Baran et al., 2020
   Live photoreceptor
  αvβ3/5 integrin Zhao et al., 2015
   Live endothelial cell
  ? Jolivel et al., 2015
   Live tumor cell
  ? Hutter et al., 2019