TABLE 2.
The univariate and multivariate cox analysis
| Characteristics | Total (N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | ||
| Age (< = 70 vs. > 70) | 407 | 1.514 (1.128−2.031) | 0.006 a | 1.165 (0.630−2.152) | 0.627 |
| Gender (Male vs. Female) | 407 | 0.874 (0.631−1.210) | 0.417 | ||
| T stage | 373 | ||||
| T1 and T2 | 122 | Reference | |||
| T stage (T1 + T2 vs. T3) | 193 | 1.917 (1.302−2.824) | < 0.001 a | 3.155 (0.702−14.182) | 0.134 |
| T stage (T1 + T2 vs. T4) | 58 | 2.867 (1.779−4.620) | < 0.001 a | 2.974 (0.616−14.354) | 0.175 |
| N stage (N0 + N1 vs. N2 + N3) | 365 | 2.240 (1.609−3.120) | < 0.001 a | 1.459 (0.684−3.112) | 0.329 |
| M stage (M0 vs. M1) | 207 | 3.310 (1.582−6.926) | 0.001 a | 1.712 (0.456−6.425) | 0.426 |
| Pathologic stage (Stage I + Stage II vs. Stage III + Stage IV) | 405 | 2.203 (1.521−3.190) | < 0.001 a | 0.416 (0.079−2.196) | 0.301 |
| Histologic grade (LG vs. HG) | 404 | 2.899 (0.717−11.718) | 0.135 | ||
| Lymphovascular invasion (No vs. Yes) | 280 | 2.249 (1.547−3.268) | < 0.001 a | 2.696 (1.316−5.522) | 0.007 a |
| DLGAP5 (Low vs. High) | 407 | 1.362 (1.013−1.831) | 0.041 a | 2.925 (1.501−5.699) | 0.002 a |
HR: Hazard ratio, LG: low grade, HG: High grade.
a
P value < 0.05.