Figure 6. STAT1-pS727 promotes TLR7-accelerated lupus nephritis.

(A) Kidney sections from 6-8 mo old Sle1b^Yaa and Sle1b^Yaa.STAT1-SA male mice were stained with anti-C3 (green) and anti-IgG (red). Representative images (B) of PAS stained kidney sections and the glomerulonephritis (GN) score (C) are shown from these mice. These data represent 7-8 mice from each group that was collected from two independent experiments. Statistical analysis was performed by two-way ANOVA, with a follow-up Sidak multiple-comparison test (h) or unpaired, nonparametric Mann-Whitney Student’s t-test. Ns, non-significant; **P < 0.01.