Skip to main content
. 2022 Jul 21;20:40. doi: 10.1186/s12959-022-00400-3

Fig. 1.

Fig. 1

Clotting time in the different thromboelastometric tests after spiking blood samples with edoxaban and apixaban. Depicted are (A) FIBTEM, (B) HEPTEM, (C) TFTEM and (D) ECATEM. Data presented as median and interquartile range. + versus baseline apixaban; $ versus baseline edoxaban; # between DOACs at this concentration. CT: clotting time; DOAC: direct oral anticoagulant; FIBTEM: analyzing the extrinsic pathway of coagulation focusing on fibrinogen status; HEPTEM: analyzing the intrinsic pathway of coagulation containing heparinase; TFTEM: low tissue factor test containing 10% of tissue factor compared to standard EXTEM/FIBTEM; ECATEM: ecarin-based test for the specific detection of direct thrombin inhibitors