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. 2022 Jul 21;21:137. doi: 10.1186/s12933-022-01570-0

Table 2.

Odds ratios and 95% CIs for the association of the TyG index with CA, CMT, plaques and stenosis

Continuous Quartiles of the TyG index P for trend
Q1 Q2 Q3 Q4
CA
 Model 1 1.94 (1.86–2.04) Ref 1.08 (0.99–1.18) 1.49 (1.37–1.62) 2.42 (2.24–2.62) < 0.001
 Model 2 1.95 (1.85–2.05) Ref 1.11 (1.01–1.22) 1.57 (1.44–1.72) 2.48 (2.28–2.70) < 0.001
 Model 3 1.48 (1.39–1.56) Ref 0.98 (0.89–1.08) 1.27 (1.15–1.40) 1.59 (1.45–1.75) < 0.001
CMT (≥ 1.00 mm)
 Model 1 1.98 (1.87–2.10) Ref 1.23 (1.10–1.39) 1.78 (1.59–1.98) 2.77 (2.49–3.07) < 0.001
 Model 2 1.93 (1.81–2.05) Ref 1.24 (1.10–1.40) 1.79 (1.60–2.01) 2.71 (2.43–3.02) < 0.001
 Model 3 1.55 (1.45–1.67) Ref 1.14 (1.01–1.29) 1.63 (1.36–1.73) 1.93 (1.82–2.18) < 0.001
Plaques
 Model 1 1.84 (1.75–1.94) Ref 1.01 (0.92–1.12) 1.23 (1.12–1.35) 2.12 (1.94–2.31) < 0.001
 Model 2 1.84 (1.74–1.94) Ref 1.04 (0.94–1.16) 1.30 (1.18–1.44) 2.17 (1.97–2.38) < 0.001
 Model 3 1.38 (1.30–1.47) Ref 0.92 (0.82–1.02) 1.03 (0.93–1.15) 1.36 (1.22–1.51) < 0.001
Stenosis (≥ 50%)
 Model 1 1.74 (1.52–1.99) Ref 0.91 (0.69–1.20) 1.46 (1.14–1.88) 2.28 (1.81–2.88) < 0.001
 Model 2 1.64 (1.43–1.89) Ref 0.86 (0.64–1.16) 1.48 (1.14–1.91) 2.11 (1.65–2.68) < 0.001
 Model 3 1.33 (1.14–1.56) Ref 0.83 (0.62–1.12) 1.34 (1.03–1.76) 1.56 (1.20–2.04) < 0.001

CA carotid atherosclerosis; CMT carotid intima–media thickness; TyG triglyceride-glucose

Model 1: Unadjusted;

Model 2: Adjusted for sex, age, education, smoke, drink, physical activity;

Model 3: Adjusted for sex, age, education, smoke, drink, physical activity, BMI, SBP, DBP, TC, LDL-C, HDL-C, history of diseases including cerebrovascular disease, heart diseases, hypertension, dyslipidemia and diabetes