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. 2022 Jul 21;21:137. doi: 10.1186/s12933-022-01570-0

Table 3.

Subgroup analyses for the association of the continuous TyG index with CA, CMT, plaques and stenosis

OR, 95% CI
CA CMT Plaques Stenosis (≥ 50%)
Sex
 Male (N = 26,197) 1.55 (1.43–1.68) 1.60 (1.46–1.76) 1.46 (1.33–1.60) 1.27 (1.04–1.56)
 Female (N = 32,926) 1.41 (1.30–1.53) 1.51 (1.36–1.67) 1.32 (1.20–1.45) 1.44 (1.13–1.84)
Age
 < 60 (N = 30,593) 1.63 (1.45–1.84) 1.70 (1.48–1.95) 1.74 (1.50–2.01) 1.47 (0.97–2.22)
 ≥ 60 (N = 28,530) 1.41 (1.32–1.50) 1.48 (1.37–1.60) 1.29 (1.20–1.39) 1.27 (1.07–1.50)
Blood pressure
 Normal (N = 28,249) 1.67 (1.49–1.88) 1.91 (1.66–2.20) 1.45 (1.27–1.66) 1.38 (1.01–1.90)
 High-normal BP (N = 14,571) 1.62 (1.43–1.83) 1.80 (1.54–2.09) 1.48 (1.28–1.71) 1.84 (1.32–2.58)
 Hypertension (N = 16,303) 1.33 (1.23–1.44) 1.33 (1.21–1.46) 1.31 (1.20–1.43) 1.13 (0.91–1.41)
BMI
 Underweight (N = 1174) 1.61 (1.01–2.57) 1.86 (1.04–3.35) 1.27 (0.76–2.12) 2.99 (0.60-14.96)
 Normal (N = 30,570) 1.36 (1.24–1.50) 1.50 (1.33–1.69) 1.21 (1.09–1.35) 1.25 (0.95–1.66)
 Overweight (N = 22,352) 1.60 (1.47–1.75) 1.64 (1.48–1.83) 1.55 (1.40–1.72) 1.48 (1.17–1.86)
 Obesity (N = 5027) 1.46 (1.27–1.67) 1.38 (1.18–1.61) 1.47 (1.27–1.71) 1.07 (0.73–1.58)

CA carotid atherosclerosis; CMT carotid intima–media thickness; BMI body mass index; TyG triglyceride-glucose

Adjusted for sex, age, education, smoke, drink, physical activity, BMI, SBP, DBP, TC, LDL-C, HDL-C, history of diseases including cerebrovascular disease, heart diseases, hypertension, dyslipidemia and diabetes