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. 2022 Jul 21;21:60. doi: 10.1186/s12944-022-01673-3

Table 4.

Partial correlation analyses for the associations between TMAO-related metabolites and lipids after rosuvastatin therapy (n = 112)

Variables TMAO Choline Carnitine Betaine GBB
r P r P r P r P r P
TG 0.076 0.434 0.051 0.598 0.003 0.978 −0.202 0.035 −0.143 0.139
TC −0.158 0.101 0.020 0.833 −0.104 0.281 −0.092 0.341 0.177 0.065
HDL-c −0.172 0.074 0.046 0.633 0.052 0.591 0.088 0.361 0.063 0.513
LDL-c −0.171 0.075 −0.071 0.460 −0.298 0.002 − 0.175 0.069 0.012 0.903
ApoA1 −0.059 0.539 0.035 0.716 −0.026 0.785 0.020 0.840 0.018 0.854
ApoB −0.122 0.205 −0.075 0.440 −0.255 0.007 −0.150 0.119 −0.068 0.484

TMAO Trimethylamine N-oxide, TG Triglycerides, TC Total cholesterol, HDL-c High-density lipoprotein cholesterol, LDL-c Low-density lipoprotein cholesterol, ApoA1 Apolipoprotein A1, ApoB Apolipoprotein B, GBB γ-butyrobetaine. Partial correlation was performed by controlling for sex, age, body mass index and estimated glomerular filtration rate.