Figure 6.

Mouse strain-specific SNP probes facilitate tracing of backcross generations

(A) Inbred mouse strain pedigree and SNP probe design. Numbers in yellow indicate the number of segregating SNPs in the whole genome, from which SNP probes were selected.

(B) Genotyping result of 27 mouse strains. Rows correspond to designed SNP probes. Columns correspond to samples. Rows are ordered such that probes that uniquely isolate a mouse strain are listed on the top, followed by probes that identify multiple strains.

(C) Strain genotyping on multiple generations of the 129Sv mice backcrossed to C57BL/6 mice. Each row corresponds to a 129/Sv-C57BL/6 segregating SNP. The fraction of 129/Sv allele is shown at the bottom.

See also Figure S7.