Table 4.
OR (95% CI) | P | |
---|---|---|
Univariable analysis | ||
Age (years) | 0.98 (0.9–1.0) | 0.11 |
Baseline BMI (kg/m2) | 1.00 (0.9–1.1) | 0.98 |
Postmenopausal | ||
No | 1 | |
Yes | 0.51 (0.2–1.4) | 0.19 |
PCOS | ||
No | 1 | |
Yes | 1.58 (0.5–5.2) | 0.45 |
T2DM | ||
No | 1 | |
Yes | 0.70 (0.3–2.0) | 0.49 |
Histology | ||
Endometrial cancer | 1 | |
Atypical hyperplasia | 2.88 (1.0–8.0) | 0.04 b |
Endometrial mass lesion | ||
No | 1 | |
Yes | 0.68 (0.2–3.1) | 0.61 |
Myometrial invasion | ||
No | 1 | |
Yes | 0.76 (1.4–4.2) | 0.75 |
Bariatric surgery | ||
No | 1 | |
Yes | 1.78 (0.6–5.2) | 0.29 |
% change in total body weighta | ||
<10% | 1 | |
≥10% | 3.26 (1.1–9.9) | 0.04 b |
Multivariable analysis adjusted for age, T2DM, histology, % change in total body weight | ||
Histology | ||
Endometrial cancer | 1 | |
Atypical hyperplasia | 3.52 (1.1–11.0) | 0.03 b |
% change in total body weighta | ||
<10% | 1 | |
>10% | 3.95 (1.3–12.5) | 0.02 b |
aExcludes the n = 5 women who progressed during progestin treatment.
bSignificant at P < 0.05.