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. 2021 Aug 4;14(11):1041–1050. doi: 10.1158/1940-6207.CAPR-21-0229

Table 4.

Clinical predictors of progestin treatment response in total cohort (n = 71).

OR (95% CI) P
Univariable analysis
Age (years) 0.98 (0.9–1.0) 0.11
Baseline BMI (kg/m2) 1.00 (0.9–1.1) 0.98
Postmenopausal
 No 1
 Yes 0.51 (0.2–1.4) 0.19
PCOS
 No 1
 Yes 1.58 (0.5–5.2) 0.45
T2DM
 No 1
 Yes 0.70 (0.3–2.0) 0.49
Histology
 Endometrial cancer 1
 Atypical hyperplasia 2.88 (1.0–8.0) 0.04 b
Endometrial mass lesion
 No 1
 Yes 0.68 (0.2–3.1) 0.61
Myometrial invasion
 No 1
 Yes 0.76 (1.4–4.2) 0.75
Bariatric surgery
 No 1
 Yes 1.78 (0.6–5.2) 0.29
% change in total body weighta
 <10% 1
 ≥10% 3.26 (1.1–9.9) 0.04 b
Multivariable analysis adjusted for age, T2DM, histology, % change in total body weight
Histology
 Endometrial cancer 1
 Atypical hyperplasia 3.52 (1.1–11.0) 0.03 b
% change in total body weighta
 <10% 1
 >10% 3.95 (1.3–12.5) 0.02 b

aExcludes the n = 5 women who progressed during progestin treatment.

bSignificant at P < 0.05.