Figure 22.

A duplication block in the 2p11 region of human chromosome 2. Each segment is labelled according the location of the presumed ancestral copy. The upper diagram shows computationally predicted ancestral loci of segments in the duplication block, and the lower diagram shows segments whose ancestral loci have been determined experimentally. (Some of the shortest segments have not been experimentally addressed.) Most of the duplicated segments come from other chromosomes. Reprinted by permission from Springer Nature: Nature Genetics, 39(11):1361–8. Ancestral reconstruction of segmental duplications reveals punctuated cores of human genome evolution, Z. Jiang et al. Copyright 2007.