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. 2022 Feb 3;20(4):845–856. doi: 10.1111/jth.15653

TABLE 3.

Linear regression analysis of ROTEM assays: unstandardised coefficients

INTEM EXTEM FIBTEM
CT CFT α‐angle MCF ML CFT α‐angle MCF MCF
Age −0.04 0.04 −0.01 0 −0.03 0.05 −0.02 0.01 0.05
Sex (Male = 1) 2.03 −4.04 0.44 0.02 −0.47 2.66 −0.32 −1.06 −1.71
Caucasian −8.94 22.94 −2.96+ −3.99+ 0.14 6.46 −1.31 −3.04+ −2.35
Black 3.09 8.35 −1.27 −2.88 0.6 4.04 −0.75 −3.02+ −3.68
Asian 0.61 14.85 −1.77 −2.4 −0.45 1.83 −0.55 −1.73 −1.37
BMI 0.27 0.41 −0.03 0.02 0.01 0.02 0 0 0.17+
HGB 0.21 −0.49* 0.04 −0.01 n/a 0.34** −0.07** −0.07** −0.15**
Platelets n/a −0.22** 0.03** 0.04** n/a −0.11** 0.02** 0.04** n/a
Urea −0.89** −0.38 0.05 −0.03 −0.06 0.07 −0.03 −0.05 0.04
eGFR −0.19+ 0.27 −0.04+ −0.09** 0.04* 0.16* −0.04* −0.06** −0.04
PAI‐1 n/a n/a n/a n/a −0.22+ n/a n/a n/a n/a
Intercept 170.42** 136.32** 70.07** 64.49** 7.25** 30.78+ 86.62** 74.92** 38.33**
Adjusted R 2 0.1 0.11 0.18 0.26 0.22 0.36 0.35 0.4 0.34
Significance 0.01 0.01 <.01 <0.01 <0.01 <0.01 <0.01 <0.01 <0.01

Abbreviations: BMI, body mass index; CFT, clot formation time; CT, clotting time; eGFR, estimated glomerular filtration rate; HGB, hemoglobin; MCF, maximum clot firmness; ML, maximum lysis; PAI‐1, platelet activator inhibitor‐1.

Notes: Significance level: **P ≤ .01; *P ≤ .05; +P ≤ .10. CT and ML were not included for EXTEM, as regression model was not statistically significant.