Figure 1.

ATP‐fueled DNA assemblies with transient functions. a) Schematic illustration of ATP‐fueled transient organization of functional motifs. b) Programmable lifetime for the fuel‐driven transient functional state. After adding ATP, the system enters into an activated state, state B, from its ground state, state A, which returns to state A once the ATP is consumed. c–e) DNA assemblies at the fuel‐driven active state for c) FRET, d) multivalent target sensing, and e) DNAzyme for substrate cleavage. The dynamic ligation/cleavage sites on the dsDNA are indicated by arrows.