TABLE 3.
Summary of renal clearance (ml/min) calculated for all analytes and participants based on the data collected up to 6 h post mephedrone administration
| Participant | MEPH | DHM | NOR | HYDROXY | 4‐carboxy | DHNM |
|---|---|---|---|---|---|---|
| M1 | 56 | 294 | 35 | 701 | 423 | 17 |
| M2 | 41 | 134 | 24 | 443 | 359 | 320 |
| M3 | 383 | 378 | 187 | 601 | 435 | 640 |
| M4 | 117 | 125 | 45 | 671 | 335 | ND |
| M5 | 44 | 94 | 28 | 540 | 448 | ND |
| M6 | 5.6 | 27 | 2.2 | 87 | 92 | 31 |
| Mean | 108 | 175 | 54 | 507 | 349 | 252 |
| SD | 140 | 132 | 67 | 226 | 133 | 294 |
Abbreviation: ND, not determined, because DHNM was not detected in plasma samples from M4 and M5.