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Model structure for cefiderocol pharmacokinetics in plasma and epithelial lining fluid (ELF). A(1) is the drug amount in the central compartment, A(2) and A(3) are the drug amounts in peripheral compartments, and C(ELF) is the ELF concentration of the drug. K is the first‐order rate constant of elimination, and K12, K21, K13, K31, KE0, and KE1 are first‐order transfer rate constants between compartments.
