FIGURE 1.

Risk of end‐stage kidney disease (ESKD) according to number of birth‐related risk factors (birth weight <10th percentile, birth weight for gestational age <10th percentile, and preterm birth). Reproduced with permission from Gjerde, Lillas, et al. (2020). The blue dotted line depicts the decrease in relative fertility rate for women from 20 to 45 years of age (Heffner, 2004). The risk of progression to ESKD for infants of low birth weight is largely delayed beyond peak reproductive years and has minimal effect on reproductive fitness