TABLE 2.

Association between selected variables and mortality based on data from the INPULSIS and INBUILD trials

	HR (95% CI)	p‐value
Selected variables in INPULSIS
Relative decline in FVC >10% predicted within 12 months	3.77 (2.28, 6.24)	<0.0001
Age	1.03 (1.00, 1.07)	0.037
FVC % predicted at baseline	0.97 (0.95, 0.99)	0.0007
DLCO % predicted at baseline	0.77 (0.61, 0.98)	0.033
Selected variables in INBUILD
HRCT pattern a	2.98 (1.23, 7.22)	0.016
Relative decline in FVC >10% predicted within 12 months	2.60 (1.28, 5.31)	0.0085
DLCO % predicted at baseline	0.95 (0.91, 0.98)	0.0046

Abbreviations: DLCO, diffusing capacity of the lungs for carbon monoxide; FVC, forced vital capacity; HR, hazard ratio; UIP, usual interstitial pneumonia.

^a HR for subjects with a UIP‐like fibrotic pattern on HRCT compared with subjects with other fibrotic patterns on HRCT.