Table 5.
Summary of results: subgroup analyses for maternal iron deficiency anemia
| Random effects model | Random effects model | ||||||
|---|---|---|---|---|---|---|---|
| Effect of MMS versus IFA on iron deficiency anemia (third trimester), Hb<110 g/L and serum ferritin<12 μg/dL for most studies | n comparisons | Risk ratio (95% CI) | P value (subgroup differences) | n comparisons | Risk difference (95% CI) | P value (subgroup differences) | Included studies |
| Subgroup analysis by iron dose | |||||||
| MMS 60 mg iron versus IFA 60 mg iron | 3 | 1.18 (0.94−1.48) | 0.76 | 3 | 0.17 (−0.06 to 0.39) | 0.76 | 12, 19, 28 |
| MMS 30 mg iron versus IFA 30 mg iron | 2 | 0.91 (0.43−1.93) | 2 | −0.10 (−0.85 to 0.66) | 27, 30 | ||
| MMS 30 mg iron versus IFA 60 mg iron | 2 | 1.31 (0.66−2.60) | 2 | 0.27 (−0.41 to 0.96) | 21, 30 | ||
| Subgroup analysis by differences in total iron intake between IFA and MMS | |||||||
| Small difference IFA‐MMS (<1200 mg) | 5 | 1.15 (0.93−1.41) | 0.71 | 5 | 0.14 (−0.07 to 0.35) | 0.71 | 12, 19, 27, 28, 30 |
| Large difference IFA‐MMS (≥1200 mg) | 2 | 1.31 (0.66−2.60) | 2 | 0.27 (−0.41 to 0.96) | 21, 30 | ||