Table 1.
Optimized MS/MS condition for target compounds.
| Compound | Precursor ion (m/z) | Product ion (m/z) | Fragmentor voltage | Collision energy | Polarity |
|---|---|---|---|---|---|
| Amlodipine | 409.1 | 237.8 | 135 | 3 | + |
| Atenolol | 267.1 | 190.1 | 135 | 13 | + |
| Atorvastatin | 559.6 | 440.2 | 175 | 17 | + |
| Digoxin | 651.3 | 131 | 160 | 24 | + |
| Enalapril | 377.1 | 234.1 | 115 | 24 | + |
| Fenofibrate | 361.0 | 233.0 | 115 | 11 | − |
| Furosemide | 329.0 | 284.9 | 110 | 10 | + |
| Losartan | 423.1 | 207.1 | 105 | 20 | + |
| Nifedipine | 347.1 | 315.1 | 90 | 3 | + |
| Propranolol | 260.4 | 116.1 | 145 | 14 | + |
| Simvastatin | 419.2 | 199.1 | 100 | 9 | + |
| Valsartan | 436.2 | 291.0 | 80 | 14 | + |